To gain a comprehensive understanding of mouse phenotypes, continuous monitoring of their activity and behavior in the absence of external stimuli is essential. Video-based systems, while effective, are often costly, labor-intensive, and susceptible to experimenter bias, as they require dedicated staff to interpret footage. Moreover, traditional temperature recording methods, which rely on intrusive devices and frequent handling, can be stressful for animals and are particularly challenging in group-housed or nocturnal settings.

The UID Mouse Matrix offers an innovative solution to these challenges, enabling seamless monitoring of both temperature and activity in socially-housed mice. This RFID-enabled system provides real-time, remote tracking of digital biomarkers—such as locomotor activity and body temperature—of one or multiple mice within their home-cage environment. By operating continuously, even during the dark phase, it allows for 24/7 observation without disturbing the animals.

The UID Mouse Matrix removes experimenter bias and delivers consistent, reliable measurements of both behavioral and physiological changes in individual animals over time. Its seamless integration with high-density IVC rack systems, including those from Innovive, enables remote monitoring even in complex housing environments. This advanced technology empowers researchers to gain deeper, more precise insights into progressive changes in mouse phenotypes, while ensuring a non-invasive, highly accurate monitoring process that minimizes disruption to the animals.