{"id":7471,"date":"2025-03-27T18:18:08","date_gmt":"2025-03-27T23:18:08","guid":{"rendered":"https:\/\/uidevices.com\/?page_id=7471"},"modified":"2025-04-20T23:05:13","modified_gmt":"2025-04-21T04:05:13","slug":"pharmacology-research","status":"publish","type":"page","link":"https:\/\/uidevices.com\/?page_id=7471","title":{"rendered":"Pharmacology Research"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1dt9m-02a86ff2d895274c58adc5f0ada2cdab\">\n.avia-section.av-1dt9m-02a86ff2d895274c58adc5f0ada2cdab{\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?fit=2058%2C1129&ssl=1);\nbackground-position:0% 100%;\nbackground-attachment:scroll;\nmargin-top:-80px;\nmargin-bottom:0px;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-1dt9m-02a86ff2d895274c58adc5f0ada2cdab main_color avia-section-default avia-no-border-styling  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class='flex_column av-m7th4zvg-b162794f794f65914c017e3c38fe318f av_one_half  avia-builder-el-2  el_after_av_hr  el_before_av_one_half  first flex_column_table_cell av-equal-height-column av-align-middle  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m7jt7ugh-ea5d3adb2f81b6d3099fe3411ef4580b\">\n#top .av-special-heading.av-m7jt7ugh-ea5d3adb2f81b6d3099fe3411ef4580b{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-m7jt7ugh-ea5d3adb2f81b6d3099fe3411ef4580b .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-m7jt7ugh-ea5d3adb2f81b6d3099fe3411ef4580b .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-m7jt7ugh-ea5d3adb2f81b6d3099fe3411ef4580b av-special-heading-h1  avia-builder-el-3  avia-builder-el-no-sibling '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Pharmacology Research<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><\/div><div class='av-flex-placeholder'><\/div><div  class='flex_column av-2ma5ce-5637cff6c024ee10ac80d630145df244 av_one_half  avia-builder-el-4  el_after_av_one_half  avia-builder-el-last  flex_column_table_cell av-equal-height-column av-align-middle  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m7th0w3c-6e88f8bd72b400ff8835e169825f131d\">\n.avia-image-container.av-m7th0w3c-6e88f8bd72b400ff8835e169825f131d img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-m7th0w3c-6e88f8bd72b400ff8835e169825f131d .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-m7th0w3c-6e88f8bd72b400ff8835e169825f131d av-styling- avia-align-center  avia-builder-el-5  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-7477 avia-img-lazy-loading-not-7477 avia_image ' src=\"https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?fit=1030%2C565&ssl=1\" alt='' title='Scientist with a tube of biological sample test by covid-19 virus with serum liquid bottle on table doctor in the laboratory science sample chemistry or medicine test'  height=\"565\" width=\"1030\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?w=2058&amp;ssl=1 2058w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=300%2C165&amp;ssl=1 300w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=1030%2C565&amp;ssl=1 1030w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=768%2C421&amp;ssl=1 768w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=1536%2C843&amp;ssl=1 1536w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=2048%2C1124&amp;ssl=1 2048w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=1500%2C823&amp;ssl=1 1500w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=705%2C387&amp;ssl=1 705w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=450%2C247&amp;ssl=1 450w, https:\/\/i0.wp.com\/uidevices.com\/wp-content\/uploads\/2025\/03\/Pharma-2058x1150-1.jpg?resize=500%2C274&amp;ssl=1 500w\" sizes=\"(max-width: 1030px) 100vw, 1030px\" \/><\/div><\/div><\/div><\/div><\/div><!--close column table wrapper. Autoclose: 1 --><\/div><\/div><\/main><!-- close content main element --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-6eau7i-47c409c640c3486a9d891070c3cff5ad\">\n.avia-section.av-6eau7i-47c409c640c3486a9d891070c3cff5ad{\nmargin-top:-80px;\nmargin-bottom:0px;\n}\n<\/style>\n<div id='av_section_2'  class='avia-section av-6eau7i-47c409c640c3486a9d891070c3cff5ad main_color avia-section-default avia-no-border-styling  avia-builder-el-6  el_after_av_section  el_before_av_one_full  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-7471'><div class='entry-content-wrapper clearfix'>\n<div  class='flex_column av-3lo5ji-9ff2c77fc83c58be580d211d21094ae2 av_two_third  avia-builder-el-7  el_before_av_one_third  avia-builder-el-first  first flex_column_div  '     ><section  class='av_textblock_section av-2qq98e-2d01ddbb42ab1318f2088b14838d7262 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p data-pm-slice=\"1 1 &#091;&#093;\">Advancements in pharmacology research demand innovative solutions to improve data accuracy, enhance efficiency, and ensure ethical animal research practices. Unified Information Devices (UID) technology is transforming preclinical pharmacology studies by enabling non-invasive, automated, and high-throughput monitoring of laboratory animals. The following content explores how UID technology supports drug development, safety pharmacology, and experimental therapeutics research.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m7jtihxv-57a187e76f9010445049ed2f61af8b6c\">\n#top .av-special-heading.av-m7jtihxv-57a187e76f9010445049ed2f61af8b6c{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-m7jtihxv-57a187e76f9010445049ed2f61af8b6c .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-m7jtihxv-57a187e76f9010445049ed2f61af8b6c .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-m7jtihxv-57a187e76f9010445049ed2f61af8b6c av-special-heading-h3 blockquote modern-quote  avia-builder-el-9  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Overview of UID Technology<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-m7jtlkqg-b5dfb502b99bb97503d84ef86c83d42d '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p data-pm-slice=\"1 1 &#091;&#093;\">UID offers cutting-edge solutions that integrate <strong>RFID-based animal identification, real-time physiological monitoring, and home cage monitoring systems<\/strong>. These technologies provide continuous, automated data collection, reducing human intervention while improving study reproducibility and compliance with the 3Rs (Replacement, Reduction, Refinement) principle.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m7jwi2zl-7cd48008e9608ec02c9e19321318ea89\">\n#top .av-special-heading.av-m7jwi2zl-7cd48008e9608ec02c9e19321318ea89{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-m7jwi2zl-7cd48008e9608ec02c9e19321318ea89 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-m7jwi2zl-7cd48008e9608ec02c9e19321318ea89 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-m7jwi2zl-7cd48008e9608ec02c9e19321318ea89 av-special-heading-h3 blockquote modern-quote  avia-builder-el-11  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Key UID Technologies:<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-m7jwiwfr-2d1b5ae5e0cefec9a8406d170819e98a '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><ul data-spread=\"false\" data-pm-slice=\"3 3 &#091;&#093;\">\n<li><a rel=\"nofollow\" title=\"Laboratory Animal Temperature\" href=\"https:\/\/uidevices.com\/laboratory-animal-temperature\/\"><strong>UID Temperature Transponders<\/strong>:<\/a> Implantable microchips that enable real-time core body temperature monitoring.<\/li>\n<li><a rel=\"nofollow\" title=\"Home Cage Monitoring\" href=\"https:\/\/uidevices.com\/home-cage-monitoring\/\"><strong>UID Home Cage Monitoring System<\/strong>:<\/a> Non-invasive tracking of activity, circadian rhythms, and behavioral patterns.<\/li>\n<li><a rel=\"nofollow\" title=\"Laboratory Animal Identification\" href=\"https:\/\/uidevices.com\/laboratory-animal-identification\/\"><strong>Automated Identification Systems<\/strong>:<\/a> RFID-based tracking ensures precise animal identification in longitudinal studies.<\/li>\n<\/ul>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m7jwo41q-599e7804a408e59b5b5c2bff7fbf0e74\">\n#top .av-special-heading.av-m7jwo41q-599e7804a408e59b5b5c2bff7fbf0e74{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-m7jwo41q-599e7804a408e59b5b5c2bff7fbf0e74 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-m7jwo41q-599e7804a408e59b5b5c2bff7fbf0e74 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-m7jwo41q-599e7804a408e59b5b5c2bff7fbf0e74 av-special-heading-h3 blockquote modern-quote  avia-builder-el-13  el_after_av_textblock  el_before_av_toggle_container '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Applications in Pharmacology Research<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m8m2jg7b-95a23c2f6f55bb8ac1fc8ca16a1b898d\">\n#top .togglecontainer.av-m8m2jg7b-95a23c2f6f55bb8ac1fc8ca16a1b898d h4.toggler{\ncolor:#77777a;\nbackground-color:#ffffff;\nborder-color:#ffffff;\n}\n#top .togglecontainer.av-m8m2jg7b-95a23c2f6f55bb8ac1fc8ca16a1b898d h4.toggler .toggle_icon{\ncolor:#77777a;\nborder-color:#77777a;\n}\n#top .togglecontainer.av-m8m2jg7b-95a23c2f6f55bb8ac1fc8ca16a1b898d h4.toggler .toggle_icon > span{\ncolor:#77777a;\nborder-color:#77777a;\n}\n#top .togglecontainer.av-m8m2jg7b-95a23c2f6f55bb8ac1fc8ca16a1b898d .toggle_wrap .toggle_content{\ncolor:#77777a;\nbackground-color:#ffffff;\nborder-color:#ffffff;\n}\n<\/style>\n<div  class='togglecontainer av-m8m2jg7b-95a23c2f6f55bb8ac1fc8ca16a1b898d av-minimal-toggle  avia-builder-el-14  el_after_av_heading  el_before_av_heading  toggle_close_all' >\n<section class='av_toggle_section av-m8m2himm-bd50033e196dc3ead254289259e5bfe7'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><h4 id='toggle-toggle-id-1' data-fake-id='#toggle-id-1' class='toggler  activeTitle av-title-above av-inherit-border-color'  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-1' data-slide-speed=\"200\" data-title=\"1. Drug Efficacy and Toxicology Studies\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: 1. Drug Efficacy and Toxicology Studies\" data-aria_expanded=\"Click to collapse: 1. Drug Efficacy and Toxicology Studies\">1. Drug Efficacy and Toxicology Studies<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/h4><div id='toggle-id-1' aria-labelledby='toggle-toggle-id-1' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color av-inherit-border-color'  itemprop=\"text\" ><ul data-spread=\"false\" data-pm-slice=\"3 3 &#091;&#093;\">\n<li><strong>Non-invasive physiological monitoring<\/strong>: Enables real-time assessment of drug effects on core body temperature, metabolism, and locomotion.<\/li>\n<li><strong>Reduced handling stress<\/strong>: Automation minimizes human interference, reducing variability in pharmacokinetic and pharmacodynamic studies.<\/li>\n<li><strong>Enhanced high-throughput screening<\/strong>: Enables continuous monitoring across multiple test subjects, optimizing data collection.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/section>\n<section class='av_toggle_section av-m8m2i23v-a7423aab1b62db273bca560b6fe65687'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><h4 id='toggle-toggle-id-2' data-fake-id='#toggle-id-2' class='toggler  av-title-above av-inherit-border-color'  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-2' data-slide-speed=\"200\" data-title=\"2. Safety Pharmacology\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: 2. Safety Pharmacology\" data-aria_expanded=\"Click to collapse: 2. Safety Pharmacology\">2. Safety Pharmacology<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/h4><div id='toggle-id-2' aria-labelledby='toggle-toggle-id-2' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color av-inherit-border-color'  itemprop=\"text\" ><ul data-spread=\"false\" data-pm-slice=\"3 3 &#091;&#093;\">\n<li><strong>Cardiovascular and metabolic assessments<\/strong>: Real-time tracking of temperature fluctuations can indicate drug-induced thermoregulatory changes.<\/li>\n<li><strong>CNS drug testing<\/strong>: Behavioral and activity monitoring aids in evaluating neuroactive compounds, sedatives, and stimulants.<\/li>\n<li><strong>Longitudinal studies with minimal disruption<\/strong>: Continuous data collection supports long-term safety assessments.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/section>\n<section class='av_toggle_section av-m8m2lnxd-88b2ad79ed6418ebf362590bee9d078c'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><h4 id='toggle-toggle-id-3' data-fake-id='#toggle-id-3' class='toggler  av-title-above av-inherit-border-color'  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-3' data-slide-speed=\"200\" data-title=\"3. Disease Model Research and Therapeutics\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: 3. Disease Model Research and Therapeutics\" data-aria_expanded=\"Click to collapse: 3. Disease Model Research and Therapeutics\">3. Disease Model Research and Therapeutics<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/h4><div id='toggle-id-3' aria-labelledby='toggle-toggle-id-3' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color av-inherit-border-color'  itemprop=\"text\" ><ul data-spread=\"false\" data-pm-slice=\"3 3 &#091;&#093;\">\n<li><strong>Metabolic Disorders<\/strong>: Supports research on diabetes, obesity, and thermoregulation by tracking temperature and activity patterns.<\/li>\n<li><strong>Pain and Inflammation Studies<\/strong>: Temperature serves as a biomarker for inflammatory responses and analgesic effects.<\/li>\n<li><strong>Neurodegenerative Disease Research<\/strong>: Identifies behavioral changes related to neurodegenerative disorders like Alzheimer\u2019s and Parkinson\u2019s.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/section>\n<section class='av_toggle_section av-m8m2m77c-2ad99860ec3c74d9855dc59884a25117'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><h4 id='toggle-toggle-id-4' data-fake-id='#toggle-id-4' class='toggler  av-title-above av-inherit-border-color'  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-4' data-slide-speed=\"200\" data-title=\"4. Dosing and Pharmacokinetics\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: 4. Dosing and Pharmacokinetics\" data-aria_expanded=\"Click to collapse: 4. Dosing and Pharmacokinetics\">4. Dosing and Pharmacokinetics<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/h4><div id='toggle-id-4' aria-labelledby='toggle-toggle-id-4' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color av-inherit-border-color'  itemprop=\"text\" ><ul data-spread=\"false\" data-pm-slice=\"3 3 &#091;&#093;\">\n<li><strong>Automated Subject Tracking<\/strong>: Ensures accurate linkage between individual animals and physiological data.<\/li>\n<li><strong>Improved Reproducibility<\/strong>: Reduces variability in drug response data through continuous, standardized monitoring.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/section>\n<section class='av_toggle_section av-m8m2mmqy-272e96436d75b93a357a1f330d77c512'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><h4 id='toggle-toggle-id-5' data-fake-id='#toggle-id-5' class='toggler  av-title-above av-inherit-border-color'  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-5' data-slide-speed=\"200\" data-title=\"5. Ethical Considerations and Regulatory Compliance\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: 5. Ethical Considerations and Regulatory Compliance\" data-aria_expanded=\"Click to collapse: 5. Ethical Considerations and Regulatory Compliance\">5. Ethical Considerations and Regulatory Compliance<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/h4><div id='toggle-id-5' aria-labelledby='toggle-toggle-id-5' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color av-inherit-border-color'  itemprop=\"text\" ><ul data-spread=\"false\" data-pm-slice=\"3 3 &#091;&#093;\">\n<li><strong>Refinement of Animal Research<\/strong>: Eliminates the need for invasive techniques, such as rectal probes, improving animal welfare.<\/li>\n<li><strong>GLP and Regulatory Compliance<\/strong>: Ensures high data integrity, supporting regulatory submissions.<\/li>\n<li><strong>Reduced Animal Use<\/strong>: Increases data collection efficiency per subject, aligning with the reduction principle of the 3Rs.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/section>\n<\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m7jtpotv-cae11a0916a5adf046660154facd206f\">\n#top .av-special-heading.av-m7jtpotv-cae11a0916a5adf046660154facd206f{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-m7jtpotv-cae11a0916a5adf046660154facd206f .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-m7jtpotv-cae11a0916a5adf046660154facd206f .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-m7jtpotv-cae11a0916a5adf046660154facd206f av-special-heading-h3 blockquote modern-quote  avia-builder-el-15  el_after_av_toggle_container  el_before_av_textblock '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Conclusion<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-m7jtq13p-18254dd0b763710af1cda6f637b1e4ee '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p data-pm-slice=\"1 1 &#091;&#093;\">UID technology is revolutionizing pharmacology research by offering <strong>automated, non-invasive, and high-precision monitoring tools<\/strong>. By integrating RFID tracking, real-time temperature sensing, and home cage monitoring, UID enhances data accuracy, supports ethical research practices, and accelerates drug discovery. As pharmacology research continues to evolve, UID solutions will play a critical role in advancing preclinical studies while ensuring the highest standards of data integrity and animal welfare.<\/p>\n<\/div><\/section><br \/>\n<section  class='av_textblock_section av-m7jwvxa0-055595e2bcb1442b5d0c531bc79a2bfe '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p data-pm-slice=\"1 1 &#091;&#093;\">For more information on implementing UID technology in your research, contact us at info@uidevices.com.<\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-b1j9a-53b93e9e18198c1f4ec8316de993ff29\">\n.flex_column.av-b1j9a-53b93e9e18198c1f4ec8316de993ff29{\nborder-width:2px;\nborder-color:#edae44;\nborder-style:solid;\nborder-radius:5px 5px 5px 5px;\npadding:20px 20px 20px 20px;\nbackground-color:rgba(237,174,68,0.35);\n}\n<\/style>\n<div  class='flex_column 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\/>\n<form action=\"https:\/\/uidevices.com\/?page_id=7471\" id=\"avia_contact_7471_1\" method=\"post\" data-fields-with-error=\"Found errors in the following field(s):\" class=\"avia_ajax_form av-form-labels-visible   avia-builder-el-20  el_after_av_heading  el_before_av_textblock   \" data-avia-form-id=\"1\" data-avia-redirect='' ><fieldset><div id='avia_1_1' class='av-form-text'><p>\n<b>Send me pricing and information for the following:<\/b><\/p>\n<\/div><p class='  first_form  form_element form_fullwidth' id='element_avia_2_1'><input  name=\"avia_2_1\" class=\"input_checkbox \" type=\"checkbox\" id=\"avia_2_1\" value=\"true\"\/><label class=\"input_checkbox_label\" for=\"avia_2_1\">UID Lab Animal Identification Microchips<\/label><\/p><p class='  first_form  form_element form_fullwidth' id='element_avia_3_1'><input  name=\"avia_3_1\" class=\"input_checkbox \" type=\"checkbox\" id=\"avia_3_1\" value=\"true\"\/><label class=\"input_checkbox_label\" for=\"avia_3_1\">UID Temperature 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id=\"avia_7_1\" value=\"true\"\/><label class=\"input_checkbox_label\" for=\"avia_7_1\">Controlled Substance Inventory System<\/label><\/p><p class='  first_form  form_element form_fullwidth' id='element_avia_8_1'><label for=\"avia_8_1\">Main species used in your studies<\/label><select  name=\"avia_8_1\" class=\"select \" id=\"avia_8_1\"><option   value='Mouse'>Mouse<\/option><option   value='Rat'>Rat<\/option><option   value='Hamster'>Hamster<\/option><option   value='Rabbit'>Rabbit<\/option><option   value='Dog'>Dog<\/option><option   value='Sheep'>Sheep<\/option><option   value='NHP'>NHP<\/option><option   value='Other'>Other<\/option><\/select><\/p><p class='  first_form  form_element form_fullwidth' id='element_avia_9_1'><label for=\"avia_9_1\" class=\"textare_label hidden textare_label_avia_9_1\">Describe your experimental need or questions<\/label><textarea  name=\"avia_9_1\" class=\"text_area \" cols=\"40\" rows=\"7\" id=\"avia_9_1\" ><\/textarea><\/p><div id='avia_10_1' 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You have the right to unsubscribe from email communications at any time.<\/p>\n<\/div><\/section><\/p><\/div>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='after_section_2'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-7471'><div class='entry-content-wrapper clearfix'><\/p>\n<div class='flex_column_table av-jbto67-8240af332f4a72f0ccb3a9ea89a06080 sc-av_one_full av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-jbto67-8240af332f4a72f0ccb3a9ea89a06080\">\n.flex_column.av-jbto67-8240af332f4a72f0ccb3a9ea89a06080{\nborder-radius:5px 5px 5px 5px;\npadding:30px 30px 30px 30px;\nbackground-color:#f1b350;\n}\n<\/style>\n<div  class='flex_column av-jbto67-8240af332f4a72f0ccb3a9ea89a06080 av_one_full  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class='av-special-heading-tag '  itemprop=\"headline\"  >Featured Publications<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<div  class='tabcontainer av-g24pb3-54e9236e86bbb2dca7056985bb85e9f2 top_tab  avia-builder-el-24  el_after_av_heading  avia-builder-el-last '>\n<section class='av_tab_section av_tab_section av-egmnpb-7b06c9d6783c8b3392e087f3031c1258'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-1-tab' class='tab active_tab' role='tab' aria-selected=\"true\" tabindex=\"0\" data-fake-id='#tab-id-1' aria-controls='tab-id-1-content'  itemprop=\"headline\" >Infectious Diseases<\/div><div id='tab-id-1-content' class='tab_content active_tab_content' role='tabpanel' aria-labelledby='tab-id-1-tab' aria-hidden=\"false\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><div class=\"highwire-cite-title\">\n<ul>\n<li class=\"highwire-cite-title\">Goldin, Kerry, et al. &#8220;Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2024): 2024-11.<\/li>\n<li>Rao, Deepashri, et al. &#8220;Host genetic diversity contributes to disease outcome in Crimean-Congo hemorrhagic fever virus infection.&#8221; (2024).<\/li>\n<li>Lee, Hye-Lim, et al. &#8220;Frequent low-impact exposure to THC during adolescence causes persistent sexually dimorphic alterations in the response to viral infection in mice.&#8221;\u00a0<i>Pharmacological Research<\/i>\u00a0199 (2024): 107049.<\/li>\n<li>Rao, Deepashri, et al. &#8220;CD8+ T-cells target the Crimean-Congo haemorrhagic fever virus Gc protein to control the infection in wild-type mice.&#8221;\u00a0<i>EBioMedicine<\/i>\u00a097 (2023).<\/li>\n<li>Sriramula, Srinivas, et al. &#8220;Emerging role of kinin B1 receptor in persistent neuroinflammation and neuropsychiatric symptoms in mice following recovery from SARS-CoV-2 infection.&#8221;\u00a0<i>Cells<\/i>\u00a012.16 (2023): 2107.<\/li>\n<li>Sriram, Srinivas, et al. &#8220;Long COVID in K18-hACE2 mice causes persistent brain inflammation and cognitive impairment.&#8221; (2022).<\/li>\n<li>Leventhal, Shanna S., et al. &#8220;Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge.&#8221;\u00a0<i>EBioMedicine<\/i>\u00a082 (2022).<\/li>\n<li>Wang, Tiecheng, et al. &#8220;Proteomic and metabolomic characterization of SARS-CoV-2-infected cynomolgus macaque at early stage.&#8221;\u00a0<i>Frontiers in Immunology<\/i>\u00a013 (2022): 954121.<\/li>\n<li>Smeyne, Richard J., et al. &#8220;COVID\u201019 infection enhances susceptibility to oxidative stress\u2013induced parkinsonism.&#8221;\u00a0<i>Movement Disorders<\/i>\u00a037.7 (2022): 1394-1404.<\/li>\n<li>Carossino, Mariano, et al. &#8220;Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression.&#8221;\u00a0<i>Biorxiv<\/i>\u00a0(2021): 2021-01.<\/li>\n<li>Subramaniam, Saravanan, et al. &#8220;Platelet proteome analysis reveals an early hyperactive phenotype in SARS-CoV-2-infected humanized ACE2 mice.&#8221;\u00a0<i>Biorxiv<\/i>\u00a0(2021): 2021-08.<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-chncyn-c2b530722528247c34e0138aefd307be'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-2-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-2' aria-controls='tab-id-2-content'  itemprop=\"headline\" >Metabolic Diseases and Thermoregulation<\/div><div id='tab-id-2-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-2-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Sass, Frederike, et al. &#8220;NK2R control of energy expenditure and feeding to treat metabolic diseases.&#8221;\u00a0<i>Nature<\/i>\u00a0(2024): 1-14.<\/li>\n<li>Park, Min Young, et al. &#8220;Targeted Deletion of Fibroblast Growth Factor 23 Rescues Metabolic Dysregulation of Diet-induced Obesity in Female Mice.&#8221;\u00a0<i>Endocrinology<\/i>\u00a0165.12 (2024): bqae141.<\/li>\n<li>Serdan, Tamires Duarte Afonso, et al. &#8220;Slit3 Fragments Orchestrate Neurovascular Expansion and Thermogenesis in Brown Adipose Tissue.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2024).<\/li>\n<li>Basu, Rashmita, et al. &#8220;Ventromedial hypothalamic nucleus subset stimulates tissue thermogenesis via preoptic area outputs.&#8221;\u00a0<i>Molecular Metabolism<\/i>\u00a084 (2024): 101951.<\/li>\n<li>Jayne, Lorna, et al. &#8220;A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2024).<\/li>\n<li>Selescu, Tudor, et al. &#8220;TRPM8-dependent shaking in mammals and birds.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2023): 2023-12.<\/li>\n<li>Lin, Lin, et al. &#8220;Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood.&#8221;\u00a0<i>Cell metabolism<\/i>\u00a035.7 (2023): 1227-1241.<\/li>\n<li>Min, Hyeon-Young, et al. &#8220;Overexpressing the hydroxycarboxylic acid receptor 1 in mouse brown adipose tissue restores glucose tolerance and insulin sensitivity in diet-induced obese mice.&#8221;\u00a0<i>American Journal of Physiology-Endocrinology and Metabolism<\/i>\u00a0323.3 (2022): E231-E241.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-a4eaun-955cb27c6950f0cfc5041d40afff9234'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-3-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-3' aria-controls='tab-id-3-content'  itemprop=\"headline\" >Animal welfare<\/div><div id='tab-id-3-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-3-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Gaskill, Brianna N., et al. &#8220;Evaluation of Thermal Support during Anesthesia Induction on Body Temperature in C57BL\/6 and Nude Mice.&#8221;\u00a0<i>Journal of the American Association for Laboratory Animal Science<\/i>\u00a063.3 (2024): 294-302.<\/li>\n<li>Ferguson, Lindsey T., et al. &#8220;A Novel Scoring System for Humane Endpoints in Mice with Cecal Ligation and Puncture-Induced Sepsis.&#8221;\u00a0<i>Comparative Medicine<\/i>\u00a073.6 (2023): 446-460.<\/li>\n<li>Zielinski, Rafal, et al. &#8220;Abstract B179: 2-Deoxy-D-glucose (2-DG) combination with ketogenic diet induces sedation and hypothermia in mice that becomes lethal.&#8221;\u00a0<i>Molecular Cancer Therapeutics<\/i>\u00a022.12_Supplement (2023): B179-B179.<\/li>\n<li>Winn, Caroline B., et al. &#8220;Automated monitoring of respiratory rate as a novel humane endpoint: a refinement in mouse metastatic lung cancer models.&#8221;\u00a0<i>PLoS One<\/i>\u00a016.9 (2021): e0257694.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-8x0vfj-67ac817d446ab3f8f0f7080f8fe7b8a2'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-4-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-4' aria-controls='tab-id-4-content'  itemprop=\"headline\" >Sepsis<\/div><div id='tab-id-4-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-4-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Carlin, Sean.\u00a0<i>STUDIES OF STREPTOZOTOCIN-INDUCED HYPERGLYCEMIA ON THE HOST RESPONSE TO SEPSIS<\/i>. Diss. 2024.<\/li>\n<li>Sharma, Neha, et al. &#8220;Impact of age on the host response to sepsis in a murine model of fecal-induced peritonitis.&#8221;\u00a0<i>Intensive Care Medicine Experimental<\/i>\u00a012.1 (2024): 28.<\/li>\n<li>Ferguson, Lindsey T., et al. &#8220;A Novel Scoring System for Humane Endpoints in Mice with Cecal Ligation and Puncture-Induced Sepsis.&#8221;\u00a0<i>Comparative Medicine<\/i>\u00a073.6 (2023): 446-460.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-7517bz-31d940db7836ce439ba864d8fb6afb7b'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-5-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-5' aria-controls='tab-id-5-content'  itemprop=\"headline\" >Physiology<\/div><div id='tab-id-5-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-5-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Bavis, Ryan W., et al. &#8220;Respiratory plasticity induced by chronic hyperoxia in juvenile and adult rats.&#8221;\u00a0<i>Respiratory Physiology &amp; Neurobiology<\/i>\u00a0333 (2025): 104386.<\/li>\n<li>Hirschberg, Pamela M., et al. &#8220;Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2024): 2024-05.<\/li>\n<li>Roths, Melissa, et al. &#8220;One day of environment-induced heat stress damages the murine myocardium.&#8221;\u00a0<i>American Journal of Physiology-Heart and Circulatory Physiology<\/i>\u00a0327.4 (2024): H978-H988.<\/li>\n<li>Blanton, Cynthia A., Hailey M. Streff, and Annette M. Gabald\u00f3n. &#8220;Effect of Dietary Enrichment with Hempseed (Cannabis sativa L.) on Blood Pressure Changes in Growing Mice between Ages of 5 and 30 Weeks.&#8221;\u00a0<i>Applied Sciences<\/i>\u00a014.17 (2024): 8006.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-5vvwj3-992649d99ac6cc2e3357d84bf6b53ae1'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-6-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-6' aria-controls='tab-id-6-content'  itemprop=\"headline\" >Pharmacology<\/div><div id='tab-id-6-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-6-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Tagne, Alex Mabou, et al. &#8220;\u03949-Tetrahydrocannabinol Alleviates Hyperalgesia in a Humanized Mouse Model of Sickle Cell Disease.&#8221;\u00a0<i>The Journal of Pharmacology and Experimental Therapeutics<\/i>\u00a0391.2 (2024): 174-181.<\/li>\n<li>Blanton, Cynthia A., Hailey M. Streff, and Annette M. Gabald\u00f3n. &#8220;Effect of Dietary Enrichment with Hempseed (Cannabis sativa L.) on Blood Pressure Changes in Growing Mice between Ages of 5 and 30 Weeks.&#8221;\u00a0<i>Applied Sciences<\/i>\u00a014.17 (2024): 8006.<\/li>\n<li>McKenna, Brandon A., et al. &#8220;A Pharmacokinetic and Analgesic Efficacy Study of Carprofen in Female CD1 Mice.&#8221;\u00a0<i>Journal of the American Association for Laboratory Animal Science<\/i>\u00a062.6 (2023): 545-552.<\/li>\n<li>Rivera-Garcia, Maria T., Rizelle Mae Rose, and Adrianne R. Wilson-Poe. &#8220;High-CBD cannabis vapor attenuates opioid reward and partially modulates nociception in female rats.&#8221;\u00a0<i>Addiction neuroscience<\/i>\u00a05 (2023): 100050.<\/li>\n<li>Lin, Lin, et al. &#8220;Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood.&#8221;\u00a0<i>Cell metabolism<\/i>\u00a035.7 (2023): 1227-1241.<\/li>\n<li>Torrens, Alexa, et al. &#8220;Comparative pharmacokinetics of \u03949-tetrahydrocannabinol in adolescent and adult male and female rats.&#8221;\u00a0<i>Cannabis and cannabinoid research<\/i>\u00a07.6 (2022): 814-826.<\/li>\n<li>Lee, Hye-Lim, et al. &#8220;Frequent low-dose \u03949-tetrahydrocannabinol in adolescence disrupts microglia homeostasis and disables responses to microbial infection and social stress in young adulthood.&#8221;\u00a0<i>Biological psychiatry<\/i>\u00a092.11 (2022): 845-860.<\/li>\n<li>Ruiz, C. M., et al. &#8220;Pharmacokinetic and pharmacodynamic properties of aerosolized (\u201cvaped\u201d) THC in adolescent male and female rats.&#8221;\u00a0<i>Psychopharmacology<\/i>\u00a0238 (2021): 3595-3605.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-4lkldr-8199ce0caecae14e01e73ec10da581a5'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-7-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-7' aria-controls='tab-id-7-content'  itemprop=\"headline\" >Nutrition<\/div><div id='tab-id-7-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-7-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Zielinski, Rafal, et al. &#8220;Abstract B179: 2-Deoxy-D-glucose (2-DG) combination with ketogenic diet induces sedation and hypothermia in mice that becomes lethal.&#8221;\u00a0<i>Molecular Cancer Therapeutics<\/i>\u00a022.12_Supplement (2023): B179-B179.<\/li>\n<li>Sparks, Chandler A., et al. &#8220;Dietary hempseed decreases femur maximum load in a young female C57BL\/6 mouse model but does not influence bone mineral density or micro-architecture.&#8221;\u00a0<i>Nutrients<\/i>\u00a014.20 (2022): 4224.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-ziwv-68c8aa5524a329fb195c9009d62d8da1'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-8-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-8' aria-controls='tab-id-8-content'  itemprop=\"headline\" >Immumnology<\/div><div id='tab-id-8-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-8-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Widmer, Katherine Marie.\u00a0<i>Use of a defined microbiota for maintenance of gnotobiotic SCID piglets<\/i>. MS thesis. Iowa State University, 2024.<\/li>\n<li>Ifediba, Marytheresa, et al. &#8220;Characterization of heterogeneous skin constructs for full thickness skin regeneration in murine wound models.&#8221;\u00a0<i>Tissue and Cell<\/i>\u00a088 (2024): 102403.<\/li>\n<li>Xu, Thomas Tongzhu.\u00a0<i>Surface display of proteins on bone marrow-derived dendritic cells induces humoral immune responses and anaphylaxis<\/i>. Harvard University, 2024.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<\/div><\/p><\/div><\/div><!--close column table wrapper. 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