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Veterinary Diversion Prevention

Find the Pattern Before More Medication Goes Missing

Drug diversion is often discovered through routine records: a late entry, an unexplained balance, or repeated waste adjustments. A consistent process helps the practice investigate early, protect the team, and meet reporting requirements when a theft or significant loss occurs.

  • Individual Sign-In
  • Weighed Transactions
  • Reviewable History

A 2014 Survey of 189 Colorado Veterinarians

  • 44% Were aware of opioid abuse or misuse by a client or staff member
  • 12% Were aware of veterinary staff opioid abuse or diversion
  • 73% Rated their veterinary-school training on opioid abuse or misuse as fair, poor, or absent
Early Review

Review the Record Before Drawing a Conclusion

The strongest signal is a pattern across inventory, transactions, and access. One discrepancy or behavior is not proof of diversion.

  • Inventory Records

    • Balance differences — Physical stock does not match the running balance.
    • Late or corrected entries — Transactions are added or changed after the shift.
    • Repeated waste adjustments — Waste, returns, or overfill corrections cluster around the same item or time.
    • Small recurring variances — Individually minor differences form a pattern over several counts.
  • Cabinet Access

    • Access outside expected duties — Cabinet openings do not line up with the user's schedule or assigned work.
    • Missing transaction context — Access has no matching patient, item, or note.
    • Shared credentials — The practice cannot determine who actually opened the cabinet.
    • Missing second approval — A transaction that requires two people has only one recorded user.
  • Staff Safety and Support

    FDA guidance lists changes such as repeated work errors, difficulty concentrating, and missed shifts as possible signs of opioid misuse. Those signs can have many causes.

    Document objective facts, follow established safety and HR procedures, and protect confidentiality. Do not diagnose or accuse someone based on a behavior alone.

If a Loss Is Found

Respond to Theft or Significant Loss

  1. Secure the Area and Preserve the Record

    Restrict access, count the affected stock, and save the transaction and access history before correcting any entries.

  2. Document What Is Known

    Record the drug, strength, dosage form, quantity, discovery time, people with access, and any related transactions. Separate confirmed facts from open questions.

  3. Notify the DEA Within One Business Day

    The registrant must notify the local DEA Field Division in writing within one business day of discovering a theft or significant loss. This initial notice does not wait for the full investigation.

  4. File DEA Form 106 Within 45 Days

    Submit a complete and accurate Form 106 electronically through the DEA's secure reporting system within 45 calendar days of discovery.

  5. Complete Other Required Reports

    For theft, contact local law enforcement. Check state veterinary and pharmacy-board rules, follow the practice's response plan, and document the control changes made afterward.

CSI-360 cabinet report showing item details, quantities, times, and the user for each transaction
Layered Controls

Connect Access, Measurement, and Review

Physical security is one layer. A prevention program also needs a record that identifies the user, the item, the measured amount, the patient, and the time.

CSI-360 brings those parts into the cabinet workflow:

  • Individual access — An RFID badge, card, fob, or wristband plus a PIN identifies the person opening the cabinet.
  • Two-person approval — Multi User Authentication can require a second approved user when the practice's policy calls for one.
  • Measured transactions — Before-and-after weights and the drug's density calculate the amount removed from the container.
  • Reviewable history — Inventory, activity, and user-access reports keep transaction details together for review.

CSI-360 supports the practice's controls; the DEA registrant remains responsible for policies, investigation, and reporting.

Common Questions

  • Is a locked cabinet enough?

    A securely locked, substantially constructed cabinet addresses the federal storage requirement in 21 CFR 1301.75(b). An effective diversion-control process also limits access, identifies each user, records transactions, and reviews variances. State rules may add requirements.

  • What counts as a "significant loss"?

    The DEA does not set one numeric threshold. Under 21 CFR 1301.76(b), the registrant considers the quantity and substance involved, access by specific people, patterns over time, investigation results, diversion potential, and local trends. Document the assessment instead of relying on the size of the discrepancy alone.

  • Do we file DEA Form 106 for every shortage?

    No. DEA Form 106 is for theft or significant loss, and the DEA reporting portal says not to use it to correct minor inventory shortages. Every discrepancy should still be documented and investigated. Apply the factors in 21 CFR 1301.76(b), check state requirements, and contact the local DEA Field Division when the classification is unclear.

  • How should we respond if a staff member may be involved?

    Start with safety and objective records. Preserve inventory, transaction, and access data; follow the practice's security and HR procedures; involve designated leadership; and protect confidentiality. A behavioral change alone is not proof of diversion and should not be treated as a diagnosis or accusation.

  • How does the CSI-360 help?

    CSI-360 records individual sign-in, RFID-identified items, weighed transactions, and user-access history in one system. It helps the practice review discrepancies sooner, but it does not determine intent or replace the registrant's responsibilities. See the CSI-360 product page, DEA Audit Readiness, and Syringe Accuracy for related details.

References

  1. Locked-cabinet requirement — 21 CFR 1301.75.
  2. Effective-controls requirement — 21 CFR 1301.71.
  3. Significant-loss factors and one-business-day notice — 21 CFR 1301.76.
  4. Electronic Form 106 and the 45-day deadline — 2023 DEA final rule.
  5. Veterinarian awareness of opioid misuse and diversion — American Journal of Public Health.
  6. Survey findings and veterinary workplace guidance — CDC/NIOSH, "The Role of Veterinarians in the Opioid Crisis".
  7. Behavioral warning-sign and theft-reporting guidance — FDA, "The Opioid Epidemic: What Veterinarians Need to Know".
  8. Electronic theft and loss reporting — DEA Theft Loss Reporting.

Strengthen the Record Behind Every Dispense

Tell us how controlled substances are stored and logged today. We'll show you how CSI-360 fits the cabinet and the team's workflow.