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Thesis Dissertation

Studies of streptozotocin-induced hyperglycemia on the host response to sepsis

Carlin, S., et al. 2024

M.Sc. Thesis, McMaster University

Summary

This thesis examined how streptozotocin-induced hyperglycemia changes the response of male and female C57BL/6 mice to fecal-induced peritonitis and sepsis. Hyperglycemic and control mice showed similar early inflammatory and coagulation responses and no difference in 48-hour survival or sepsis severity, but protein C patterns suggested a later shift in coagulation. UID UCT-2112 temperature microchips and a URH-1HP reader supported monitoring and identification.

Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.

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