Summary
This study tested the safety limit of combining a ketogenic diet with the glycolysis inhibitor 2-deoxy-D-glucose in CD-1 mice. Doses tolerated on standard chow caused dose-dependent sedation, profound hypothermia, breathing difficulty, thrombocytopenia, interstitial pneumonia, and rapid death on the ketogenic diet, warning that the proposed anticancer combination can create severe metabolic toxicity. UID UCT-2112 microchips, a URH-1HP reader, and Mouse Matrix captured temperature decline.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.