Summary
This study developed a visual humane-endpoint score for male and female C57BL/6J mice with cecal ligation and puncture-induced sepsis. Respiratory status, activity and stimulus response, and eye appearance showed strong observer agreement and distinguished survivors from nonsurvivors; activity-response and eye scores were especially predictive of imminent death. UID UCT-2112 temperature transponders and a URH-1HP reader added an objective temperature measure.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.