Summary
This review examines continuous, non-invasive home-cage monitoring as a source of translational digital biomarkers in preclinical drug development. Repeated measurements in a familiar environment can reveal disease progression and treatment effects while reducing handling stress and supporting the 3Rs. The authors survey available technologies, use cases, implementation barriers, data consistency, and the standards needed for broader adoption.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.