Summary
The study tracked male and female C57BL/6 mice infected with Plasmodium chabaudi or P. berghei to refine humane endpoints in malaria studies. Falling temperature and home-cage activity closely followed rising parasitemia and appeared several days before peak parasitemia and weight loss. A UID Matrix system with implanted temperature transponders continuously recorded each mouse's identity, location, movement, and temperature without removing it from the cage.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.