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Journal Article

A Pharmacokinetic and Analgesic Efficacy Study of Carprofen in Female CD1 Mice

McKenna, et al. 2023

JAALAS

Summary

This study tested higher carprofen doses for postoperative pain control in female CD1 mice. Doses of 10 and 20 mg/kg maintained proposed therapeutic plasma levels for at least twelve and twenty-four hours, but after ovariectomy carprofen mainly reduced arched posture at eight hours and the higher efficacy dose did not consistently outperform the standard regimen across behavioral measures. UID UCT-2112 microchips supported activity monitoring.

Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.

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