Summary
This methods chapter explains how to build humanized patient-derived xenograft models in immunocompromised mice for preclinical cancer studies. Pairing human tumors with a reconstituted human immune system preserves more of the tumor's biological complexity and enables testing of immunotherapies and treatment combinations. UID UC-2112 programmable microchips were used for animal identification.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.