Summary
This study sought an objective humane endpoint for BALB/c and C57BL/6 mice with metastatic lung tumors. Continuous cage monitoring showed respiratory rate increasing to roughly 1.3-1.5 times baseline before locomotion declined one to two days later, while body weight remained comparatively uninformative, giving staff time to intensify observation or euthanize before terminal distress. UID UC-2112 identification and UCT-2112 temperature microchips complemented the respiratory and activity data.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.