Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet

Summary

This study tested whether dietary grape powder could offset effects of a high-fat Western-pattern diet in female C57BL/6J mice. Grape supplementation substantially altered liver gene-expression pathways related to oxidative stress, detoxification, and fatty-acid handling, reduced non-alcoholic fatty liver changes, and was associated with longer survival. UID UC-2112 programmable microchips and a URH-1HP reader provided individual identification.

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