Summary
This dissertation developed models of neurologic disease caused by Nipah virus and highly pathogenic H5N1 influenza. African green monkeys reproduced human-like Nipah neuropathology, intracranial hamster infection did not, and dexamethasone reduced lung damage without improving survival; bovine H5N1 was strongly neurotropic in mice, while multiple H5N1 strains infected human cerebral organoids. UID UCT-2112 temperature microchips supported monitoring in the mouse work.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.