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Journal Article

Concurrent consumption of ethanol and corticosterone during adolescence alters neuroimmune sensitivity in Sprague Dawley rats

Lutzke, Ashley, et al. 2025

Addiction Neuroscience

Summary

This study modeled chronic adolescent stress and alcohol exposure by giving Sprague-Dawley rats intermittent ethanol with corticosterone through early adulthood. The highest corticosterone dose increased hippocampal IL-6 after restraint without changing blood-brain barrier permeability; ethanol delayed recovery from hypothermia in females, while low corticosterone suppressed viral-mimic fever in males. UID UCT-2112 temperature microchips and a URH-1HP reader measured thermal responses.

Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.

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