Summary
This study compared acute and repeated THC pharmacokinetics in adolescent and adult male and female rats. Adults reached higher plasma THC after the high dose, while adolescents had substantially higher brain concentrations and brain-to-plasma ratios; age and sex also changed active and inactive metabolite exposure, helping explain different behavioral responses. Abdominal UID UCT-2112 temperature microchips and a URH-1HP reader measured THC-induced thermal effects.
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