Summary
This study tested two-, six-, and seven-strain defined gut-microbiota mixtures in cesarean-derived gnotobiotic severe combined immunodeficient piglets. All three consortia were safe, microbiota composition changed with piglet age rather than SCID genotype, and the seven-strain community remained most stable over time, supporting its adoption for more reproducible SCID-pig husbandry and biomedical models. UID UCT-2112 temperature microchips supported piglet monitoring.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.