Summary
This poster developed a reproducible, mild-severity cecal ligation and puncture model of sepsis-associated acute lung injury in male C57BL/6NJ mice. The model produced about 75% survival together with pulmonary edema, vascular leak, neutrophil infiltration, and inflammatory pathway activation, supporting a seven-day ALI/ARDS study window. A UID RFID microchip system tracked body temperature and activity to help define humane endpoints.
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