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Mesenchymal Stromal Cell Therapy Restores Intestinal Integrity and Attenuates Inflammation in a Preterm Piglet Model of Necrotizing Enterocolitis

Lee, Jasmine, et al. 2025

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Summary

This study tested mesenchymal stromal cell therapy in preterm piglets with feeding-induced necrotizing enterocolitis, a model chosen for its similarity to premature human infants. A medium intraperitoneal dose improved clinical scores and reduced gross and microscopic intestinal injury, while tissue and cytokine analyses indicated restored intestinal integrity and reduced inflammation. UID UCT-2112 temperature microchips supported clinical monitoring of the piglets.

Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.

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