Summary
This study compared three- and twelve-month-old C57BL/6 mice in a fecal-induced peritonitis model that included pain relief, antibiotics, and fluids. Older septic mice developed greater inflammation and lung injury early and had 89% mortality over seventy-two hours versus 42% in young mice, demonstrating that age substantially changes outcome even with clinically relevant supportive care. UID UCT-2112 temperature microchips supported disease monitoring.
Summary written by UID from the published work. Read the original publication for the authors' abstract and full methods.